… destruction and inhibit osteoclastic differentiation. This study aimed to determine whether
mangiferin directly affects osteoblast and osteoclast proliferation and differentiation, and gene …

… by Mangiferin. Mangiferin relieved osteoporosis in OVX mice without causing severe organ
damage. This study concluded that Mangiferin promoted osteogenic differentiation of MC3T3-…

… Mangiferin (MAG) attracted our attention as a result of its potent antioxidant activity. MAG is a
… indicated that MAG positively regulates the chondrogenic and hypertrophic differentiation of …

Mangiferin (MAG) is a polyphenolic compound present in mangoes. This compound suppresses
inflammation and decreases bone destruction. This study aimed to determine whether …

… of osteoblastic bones. Mangiferin suppresses cell differentiation into ripe osteoclast and …
mRNA in BMM, thereby, Mangiferin potentially inhibits the absorption of osteoclastic bones. …

… elements that boost osteoblastic differentiation. Runx2 particularly is bonded to the Osx
promoter section regulating osteoblast differentiation in vitro and in vivo, also regulates Osx, …

… BMP2 promotes osteoblast differentiation by … Mangiferin has the potential to promote
osteoblastic bone formation by promoting cell proliferation and inducing cell differentiation in …

… Whereas resorption is associated with the degradation of calcium as a process of bone
resorption in the form of minerals facilitated by osteoclasts.Therefore, the ability of mangiferin to …

… Osteoclastogenesis assay and luciferase reporter gene assays identified that mangiferin,
naringin and nitidine chloride could suppress osteoclast differentiation. Also they have the …

… This is consistent with the reports by others showing that mangiferin positively regulates
osteoblast differentiation and suppresses osteoclastogenesis, bone resorption, and RANKL-…